Ceramic 3D-Printing for Fast, Safe and Cheaper Production of Vaccines

Production is therefore often slow and very expensive. The project NESSIE addresses precisely these weaknesses. NESSIE was initiated by SINTEF, a Norwegian research organisation, Lithoz/AT, one of the world market leaders in 3D-printing of ceramics, and IBET, a Portuguese biopharmaceutical research centre. genIbet and Cerpotech joined the consortium bringing their ex­pert­ise on manufacturing of biopharmaceuticals and innovative materials, respectively. The project aims to increase the efficiency with which vaccines are produced and is already contributing to the development of novel methods to purify viruses, such as adenovirus. Adenoviruses are excellent vectors for delivering genes or vaccine antigens to humans. Many of the successful vaccines actually use viruses to deliver the necessary elements to get immune. Such viruses are expensive to produce. Furthermore like many substances used for humans, there is extra caution with the purity and purification of these viruses is very expensive. Using ultra-high resolution ceramic 3D-printing and applying a novel design for the manufacture of chromatographic columns (the most advanced purification technology), the project will improve separation and reduce production costs. NESSIE succeeded in the production of the first chromatographic supports and will soon test them for adenovirus purification.

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